题目：Photochemical Mn-Mediated Generation of Azide Radicals for Improvement of Alkene Hydroxyazidation

作者：Chen-Xi Xia, Ziyang Li, Ruyi Ye, Zhao-Juan Wu, Yue Ren, Kuai Wang*, and Ling-Guo Meng*

单位：Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, College of Chemistry and Materials Science, Huaibei Normal University, Huaibei, Anhui 235000, P.R. China

摘要：State-of-the-art strategies for alkene-hydroxyazidation, which yield a mixture of β-azido alcohol and β-azido peroxide, must rely on phosphine reagents to improve the chemoselectivity. To overcome the above problems, we present a photochemical hydroxyazidation of alkenes via Mn-mediated ligand-to-metal charge transfer (LMCT) in O₂, which activates N₃^– to •N₃ and incorporates O₂ to be used as an oxygen source in the hydroxyazidation products. Broad alkene range and step-economy chemistry for the hydroxyazidation transformation were also demonstrated.

影响因子：5.2

分区情况：一区

链接：https://pubs.acs.org/doi/10.1021/acs.orglett.4c00911